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Funding Research and Awareness for Ovarian Cancer

Foundation News

Here at Kaleidoscope of Hope, we’re always taking steps to educate women about ovarian cancer through various forms of activism. In Foundation News you’ll find information on our events, our organization, our board of directors, and any new KOH information.



In December 2015, in an article in the Journal of Clinical Oncology Dr Rachel Grisham,2016 KOH Grant Award Winner, reported on one patient in the study we support. She found that low grade ovarian cancer can experience a response to Mek inhibitors.
 

 KOH Board Members at MMC's Ovarian Cancer Survivors Course

Morristown Medical Center was the host for the Foundation for Women’s Cancer all day Ovarian Cancer Survivors Course on Saturday, September 26, 2015.   This event attracted more than 100 attendees.  Kaleidoscope of Hope Board members, Lynn Franklin (below on left) and Lynn Stahl (below on right), hosted an informational table at this event where audience members had the opportunity to learn about the mission of Kaleidoscope of Hope and chat with two of our Board members.


 Proclamation Declares September is Ovarian Cancer Awareness Month in Somerset County, NJ

Sept. 8th -  Freeholder Mark Caliguire (l) presents to KOH Board Member Lynn Stahl (center) and Vice President Lynn Franklin (r) a Proclamation declaring September as Ovarian Cancer Awareness Month in Somerset County.  September is known nationally as Ovarian Cancer Awareness Month. 


 Ffoster has Puppies

On June 26th, 2015, Ffoster, sponsored by KOH, had a litter of 6 puppies.  This litter is part of a Cooperative Research Agreement with DHS/TSA which is built on over 10 years of puppy evaluation data and will allow us to compare WDC early puppy development to historical performance data.

Ffoster's breeding represents a new collaboration involving both TSA's Mmartino and CCI's DaVinci as the sires. We will be paternity testing the pups to determine which pups came from which sire

See more about Ffoster and related reserach on our website (see right and Funded Research)  and visit the PennVet website for more info
 


 New Genetic link to lethal ovarian cancer has potentially been identified

 Aggressive Ovarian Cancer May Be Caused by a Single Gene Mutation

By Jim Stallard, MA, Writer/Editor  |  Tuesday, April 1, 2014

Memorial Sloan Kettering researchers have identified a genetic mutation that appears to cause a rare but very aggressive type of ovarian cancer in young women. The discovery could be an important step toward developing the first effective treatments for the disease, called small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). Funded initially by a charitable organization, the research is also an example of the powerful effect philanthropy can have on rare diseases.

“There are many examples of women in their late teens or early 20s dying quickly from this disease,” says gynecologic oncologist Douglas Levine, who led the research. “The median age at diagnosis is 23, and they usually die within two years — it’s devastating. Finding the cause and a possible target could be a major advance because current therapies have very little effect.”

....Using human cancer cells, Dr. Levine and colleagues then demonstrated that SMARCA4 plays a functional role in promoting or blocking cancer growth. Inactivating SMARCA4 increased cancer growth, while boosting its expression slowed it down. This buttresses the theory that the SMARCA4 mutation is key to the rare disease.

“I don’t know of many cancers where there’s one gene that is universally mutated and seems to be driving the disease,” Dr. Levine says. “One of our next steps will be to investigate whether this one mutation is actually sufficient to transform any type of ovarian cell into a cancer cell, or whether other factors are involved.”
READ THE FULL ARTICLE
   

KOH Grant Funds Innovative Research

Dogs help sniff out ovarian cancer in Pennsylvannia Study



Nov 18, 2013 KOH visited Penn Vet Working Dog facility. They watched as three dogs were being trained to pick out the ovarian cancer tissue sample. 

 


KOH provided a grant to help fund this research.


 
 

In this Thursday, Aug. 1, 2013 photo, Jonathan Ball practices with Tsunami in the first round of training for a study that will eventually involve detecting cancerous tissue at Penn Vet Working Dog Center in Philadelphia. 
Researchers trying to develop a diagnostic tool for ovarian cancer are hoping dogs' keen sense of smell will lead them down the right path.
An early detection device that combines old-fashioned olfactory skills, chemical analysis and modern technology could lead to better survival rates for the disease, which is particularly deadly because it's often not caught until an advanced stage.

The ovarian cancer detection study is being funded by an $80,000 grant from the Madison, N.J.-based Kaleidoscope of Hope Foundation

Click to Read Full AP Article
 


WINGS OF HOPE
 KOH is honored that our President, Carole Fagella, is the recipient of the Cancer Support Community of Central NJ's Spirit of Courage award this year.  Carole's battle with O/C continues and so does her never ending activism in the fight against this disease and her tireless efforts to educate others about O/C. 


KOH's Lynn Franklin (left) with Carole Fagella (right)

 

KOH Funds Grants

KOH Funded a Grant That is a Published Poster Display at the 2012 Society of Gynecologic Oncology and at the 2012 National Annual Meeting of the Association of Clinical Oncology

KOH's Scientific Advisory Board chooses our grant recipients with great care and knowledge.  Proof lies with the American Society of Clinical Oncology's choice for a display at their 2012 National meeting presented by MSKCC researchers with funding from KOH - research which was supported by a grant from KOH!  click to view summary

Pictured above is Dr. David Hyman, recipient of 2011 KOH Grant Award
 


KOH 2010 Grant Recipient Honored by SGO

Dr. Sarah Adams, of the University of Pennsyvania Medical Center, was honored by the Society of Gynecologic Oncologists for her research project at SGO's 2012 Annual Meeting. Dr. Adams presented a power point presentation outlining her research with BRCA tumors.  Dr. Adam's ovarian cancer research was funded by a grant from KOH.

Click to view PowerPoint Presentation
 

KOH is very proud of its Scientific Advisory Committee and the brilliant researchers it selects to give financial grants to each year.


Presentation of $15,000 check to Community Medical Center- Toms River

 In 2012, KOH donated $15K to the Community Medical Center in Toms River, NJ.
Pictured above from Left to Right are: Kathy Lynch, Stephanie Bloom, Mariclaire Scott, Janice Carey
Stephanie Bloom is President and Chief Executive Officer at Community Medical Center-
This money donated by KOH will be used to assist with robotic gynecological oncology surgery for women!




KOH Board Member Participates in Annual Survivorship Garden:   KOH Board Member Janice Carey represents KOH on June 6, 2013  at the annual planting of the Survivorship Garden ouside of the Jersey Shore University Medical Center.
 



KOH Receives Donation[Allendale Women's Club donates to KOHNJ : 
The Allendale Women's Club hosted a fundraising walk in September 2012 in loving memory of one of their members who lost her battle with ovarian cancer.  Proceeds from their walk were given to KOH.  KOH board member Pat Castle (far right) accepts the check from Allendale Women's Club members Maureen Mamunes, Cheryll Vellek, and Rosemary Summers.  KOH will use this generous donation to fund research and increase awareness of ovarian cancer.



KOH Donates $5K to the Jersey Shore Medical Center
Pictured left as KOH donates $5K in 2012 to the Jersey Shore Medical Center in Neptune, NJ
L-R: Janine Triano, Joanne DiNapoli, Janice Carey, Amy Starling, Lorraine Parker, Rosanne Ryan, Mariclaire Scott, Kathy Lynch, Laura Zimmerman(oncology nurse), Robert Wahlers, Carole Fagella (KOH VP), Craig Rosati (KOH Pres.)


A  2009 KOH Young Investigator Grant Award winner,Selvendiran Karuppaiyah, PhD published the results of his research in the September issue of the Journal of Molecular Cancer Research. Click here to read an abstract.  


KOH Board Member Participates in Annual Survivorship Garden:   KOH Board Member Janice Carey represents KOH on June 6, 2013  at the annual planting of the Survivorship Garden ouside of the Jersey Shore University Medical Center.
 



KOH Receives Donation[Allendale Women's Club donates to KOHNJ : 
The Allendale Women's Club hosted a fundraising walk in September 2012 in loving memory of one of their members who lost her battle with ovarian cancer.  Proceeds from their walk were given to KOH.  KOH board member Pat Castle (far right) accepts the check from Allendale Women's Club members Maureen Mamunes, Cheryll Vellek, and Rosemary Summers.  KOH will use this generous donation to fund research and increase awareness of ovarian cancer.



KOH Donates $5K to the Jersey Shore Medical Center
Pictured left as KOH donates $5K in 2012 to the Jersey Shore Medical Center in Neptune, NJ
L-R: Janine Triano, Joanne DiNapoli, Janice Carey, Amy Starling, Lorraine Parker, Rosanne Ryan, Mariclaire Scott, Kathy Lynch, Laura Zimmerman(oncology nurse), Robert Wahlers, Carole Fagella (KOH VP), Craig Rosati (KOH Pres.)







A  2009 KOH Young Investigator Grant Award winner,Selvendiran Karuppaiyah, PhD published the results of his research in the September issue of the Journal of Molecular Cancer Research. Click here to read an abstract.