Ovarian Cancer Research News
Researchers as well as national and local organizations frequently release new information on ovarian cancer, the statistics about it, and new developments in the fight against it. This is where you’ll find the latest news.
Selvendiran Karuppaiyah, PhD, is a former KOH (2008) grantee and senior author of this recently published study In Oncogene
"Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target"
2011 KOH award winner Dr Hyman, Director of Developmental Therapeutics at Memorial Sloan Kettering , is quoted in this article on Precision Medicine use vs chemotherapy.
This is KOH research grant dollars at work! Watch this incredible news broadcast.
New genetic link to lethal ovarian cancer has potentially been identified. Read the research - watch the video
NBC NIGHTLY NEWS
Featured on the July 7, 2014 NBC Nightly News is the UPENN Vet Program which KOH is supporting with its sponsorship of Ffoster, one of 4 dogs being trained to detect the presence of ovarian cancer through smell.
KOH Supported Research in the News
FOX NEWS reports on this 5/2/13
2013 Award Winner Dr. George Preti, a Research Scientist from the Monell Chemical Senses Center collaborataes with UPENN to study if dogs can be trained to sniff out ovarian cancer.
UPENN posts article on 5/1/2013
Dogs help sniff out ovarian cancer in Pennsylvania studyFriday August 9, 2013, 7:24 AMKATHY MATHESON
PHILADELPHIA (AP) — Researchers trying to develop a diagnostic tool for ovarian cancer are hoping dogs' keen sense of smell will lead them down the right path.
An early detection device that combines old-fashioned olfactory skills, chemical analysis and modern technology could lead to better survival rates for the disease, which is particularly deadly because it's often not caught until an advanced stage.
Using blood and tissue samples donated by patients, the University of Pennsylvania's Working Dog Center has started training three canines to sniff out the signature compound that indicates the presence of ovarian cancer.
If the animals can isolate the chemical marker, scientists at the nearby Monell Chemical Senses Center will work to create an electronic sensor to identify the same odorant.
"Because if the dogs can do it, then the question is, Can our analytical instrumentation do it? We think we can," Monell organic chemist George Preti said.
More than 20,000 Americans are diagnosed with ovarian cancer each year. When it's caught early, women have a five-year survival rate of 90 percent. But because of its generic symptoms — weight gain, bloating or constipation — the disease is more often caught late.
About 70 percent of cases are identified after the cancer has spread, said Dr. Janos Tanyi, a Penn oncologist whose patients are participating in the study. For those women, the five-year survival rate is less than 40 percent, he said.
The Philadelphia researchers will build on previous work showing that early stage ovarian cancer alters odorous compounds in the body. Another study in Britain in 2004 demonstrated that dogs could identify bladder cancer patients by smelling their urine.
Dr. Leonard Lichtenfeld, deputy chief medical officer for the American Cancer Society, said while the canine concept has shown promise for several years, there haven't been any major breakthroughs yet.
"We're still looking to see whether something could be developed and be useful in routine patient care, and we're not there yet," said Lichtenfeld, who is not involved in the study.
Cindy Otto, director of the Working Dog Center, hopes to change that with the help of McBaine, a springer spaniel; Ohlin, a Labrador retriever; and Tsunami, a German shepherd.
"If we can figure out what those chemicals are, what that fingerprint of ovarian cancer is that's in the blood — or maybe even eventually in the urine or something like that — then we can have that automated test that will be less expensive and very efficient at screening those samples," Otto said.
Ovarian cancer patient Marta Drexler, 57, is heartened by the effort. Drexler describes herself as a textbook case of the disease not being detected early enough because she had no symptoms.
After two surgeries and two rounds of chemotherapy, Drexler said she didn't hesitate when Dr. Tanyi, her physician, asked her to donate tissue to the study. Last week, she visited the Working Dog Center to meet the animals whose work might one day lead to fewer battles like hers.
"To have the opportunity to help with this dreadful disease, to do something about it, even if it's just a tiny little bit of something, it's a big thing," said Drexler, of nearby Lansdowne.
The ovarian cancer detection study is being funded by an $80,000 grant from the Madison, N.J.-based Kaleidoscope of Hope Foundation.
UPENN Vet Working Dog Center Collaborating on Ovarian Cancer Detection Study 5/1/2013
KOH provides a grant to support the research on dogs being able to sniff for ovarian cancer
FOX NEWS 5/2/2013
Can Dogs Sniff Out Cancer?
KOH provides a grant to support the research of Dr. George Preti - Fox News interviews on this subject:
Ovarian Cancer: A Call for State Action.
N.J.ranks 14th in nation for ovarian cancer care
Friday July 6, 2012, 7:38 PM
BY BARBARA WILLIAMS STAFF WRITER The Record
New Jersey was ranked 14th in the nation for providing care to women with ovarian cancer, according to an alliance that advocates for women with the disease.
In the first report of its kind, the Ovarian National Alliance rated each state and District of Columbia based on laws, policies and programs that affect ovarian cancer patients.
Among the conditions that put New Jersey in the top quarter of the states are state laws that allow women to be covered by insurance for a second opinion, the routine costs of care for clinical trials and off-label use of drugs, according to the report.
State government also supports research through the sales of license plates raising awareness of cancer and a voluntary tax contribution dedicated to cancer research.
But state law does not guarantee coverage of diagnostic tests.
More than 710 women in New Jersey and 22,280 nationwide will be diagnosed with ovarian cancer this year. The disease, which has no early detection test and is often terminal, affects one in 71 women.
The report noted that where a woman lives will affect her access to health care and support services for her illness.
“Every state has room for improvement when it comes to women with ovarian cancer,” Cara Tenenbaum, vice president of policy at the alliance, said in a written statement. “Legislators in New Jersey could support women with ovarian cancer by guaranteeing coverage of medically appropriate diagnostic tools, especially for high-risk women.”
States with the best care for women with ovarian cancer included California, Maryland, Wisconsin, Illinois, and Oregon. Those at the bottom of the list were Wyoming, North Dakota, Idaho, Tennessee, and Mississippi.
To review the entire report, go to ovariancancer.org/report-card.
Email: email@example.com Alison Silberman Advocacy Outreach Coordinator
Ovarian Cancer National Alliance
901 E Street NW, Suite 405
Washington, DC 20004
How does your state rank on ovarian cancer? Our first-of-its-kind report card rates all 50 states and the District of Columbia based on four key categories that affect women with this disease. Explore your state’s rank and learn how you can take action.
KOH Supported Research In The News
2009 Award Winner Selva Selvendiran Karuppaiyah, PhD, a Research Scientist from Davis Heart & Lung Research Institute at The Ohio State University recently published an article in the Molecular Cancer Therapeutics Journal. Click here to read the article.
Most women with ovarian cancer, which kills 15,000 Americans a year, receive inadequate care and miss out on treatments that could add a year or more to their lives, a study found. Karen Mason was treated by a gynecologic oncologist after her sisters overruled her plans to have her gynecologist operate. KOH recommends you read this article written by Denise Grady and published in the NY Times on March 11, 2013.
Click to view the full article at nytimes.com
ASCO Annual Meeting - June 2010
OCNA presents a summary of the research presented at the ASCO annual meeting in June 2010.